Nicastrin Protein, Human (HEK293, His),Human,HEK293
Nicastrin Protein, a crucial gamma-secretase complex subunit, catalyzes intramembrane cleavage of Notch receptors and APP.Operating in Notch and Wnt signaling, the complex modulates regulatory proteins and CTNNB1 levels.Collaborating with PSEN1/2, APH1A/B, and PSENEN/PEN2, Nicastrin binds to proteolytically processed C83 and C99 fragments, emphasizing its pivotal role in molecular pathways and cellular processes.Nicastrin Protein, Human (HEK293, His) is the recombinant human-derived Nicastrin protein, expressed by HEK293 , with C-His labeled tag.
Molekulargewicht:
Approximately 105-125 kDa
Reinheit:
98
Formel:
23385(Gene_ID)Q92542-1 (N34-E669)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten