Nicastrin, Human (HEK293, His)

Product Overview

• Article Name: Nicastrin, Human (HEK293, His)
• Biozol Catalog Number: MCE-HY-P74698
• Supplier Catalog Number: HY-P74698
• Alternative Catalog Number: MCE-HY-P74698-100UG,MCE-HY-P74698-10UG,MCE-HY-P74698-5UG,MCE-HY-P74698-50UG
• Manufacturer: MedchemExpress
• Category: Proteine/Peptide
• Alternative Names: Nicastrin Protein, Human (HEK293, His),Human,HEK293

Product Description

Nicastrin Protein, a crucial gamma-secretase complex subunit, catalyzes intramembrane cleavage of Notch receptors and APP.Operating in Notch and Wnt signaling, the complex modulates regulatory proteins and CTNNB1 levels.Collaborating with PSEN1/2, APH1A/B, and PSENEN/PEN2, Nicastrin binds to proteolytically processed C83 and C99 fragments, emphasizing its pivotal role in molecular pathways and cellular processes.Nicastrin Protein, Human (HEK293, His) is the recombinant human-derived Nicastrin protein, expressed by HEK293 , with C-His labeled tag.

Product Properties

• Molecular Weight: Approximately 105-125 kDa
• Purity: 98
• Formula: 23385(Gene_ID)Q92542-1 (N34-E669)(Accession)

Application Notes

• Application Notes: MCE Product type: Recombinant Proteins