IFN-alpha/beta R2, Human (HEK293, hFc)

Produktübersicht

• Artikelname: IFN-alpha/beta R2, Human (HEK293, hFc)
• Artikelnummer: MCE-HY-P74860
• Hersteller Artikelnummer: HY-P74860
• Alternativnummer: MCE-HY-P74860-10UG,MCE-HY-P74860-100UG,MCE-HY-P74860-50UG
• Hersteller: MedchemExpress
• Kategorie: Proteine/Peptide
• Alternative Synonym: IFN-alpha/beta R2 Protein, Human (HEK293, hFc),Human,HEK293

Produktbeschreibung

IFN-alpha/beta R2, one of the subunit of IFN-alpha/beta receptor, is a type I IFN receptor. IFN-alpha/beta R2 forms the heterodimeric receptor with IFNAR1, and binds to type I IFNs[1]. IFN-alpha/beta R2 also interacts with JAK1 and leads to tyrosine phosphorylation of the IFNARs and STAT proteins[2]. Upon activation by these IFNs, IFNAR1 and IFN-alpha/beta R2 undergo a conformational change to promote a cascade of downstream signaling events, including the phosphorylation of Tyk2 and JAK1, STAT1 and STAT2[3]. IFN-alpha/beta R2 Protein, Human (HEK293, hFc) is a recombinant human IFN-alpha/beta R2 (I27-K243) with C-terminal hFc tag, which is produced in HEK293 cells.

Produkteigenschaften

• Molekulargewicht: 65-75 kDa
• Reinheit: 96
• Formel: 3455(Gene_ID)P48551-1 (I27-K243)(Accession)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Recombinant Proteins