IFN-alpha/beta R2, Human (HEK293, hFc)

Product Overview

• Article Name: IFN-alpha/beta R2, Human (HEK293, hFc)
• Biozol Catalog Number: MCE-HY-P74860
• Supplier Catalog Number: HY-P74860
• Alternative Catalog Number: MCE-HY-P74860-10UG,MCE-HY-P74860-100UG,MCE-HY-P74860-50UG
• Manufacturer: MedchemExpress
• Category: Proteine/Peptide
• Alternative Names: IFN-alpha/beta R2 Protein, Human (HEK293, hFc),Human,HEK293

Product Description

IFN-alpha/beta R2, one of the subunit of IFN-alpha/beta receptor, is a type I IFN receptor. IFN-alpha/beta R2 forms the heterodimeric receptor with IFNAR1, and binds to type I IFNs[1]. IFN-alpha/beta R2 also interacts with JAK1 and leads to tyrosine phosphorylation of the IFNARs and STAT proteins[2]. Upon activation by these IFNs, IFNAR1 and IFN-alpha/beta R2 undergo a conformational change to promote a cascade of downstream signaling events, including the phosphorylation of Tyk2 and JAK1, STAT1 and STAT2[3]. IFN-alpha/beta R2 Protein, Human (HEK293, hFc) is a recombinant human IFN-alpha/beta R2 (I27-K243) with C-terminal hFc tag, which is produced in HEK293 cells.

Product Properties

• Molecular Weight: 65-75 kDa
• Purity: 96
• Formula: 3455(Gene_ID)P48551-1 (I27-K243)(Accession)

Application Notes

• Application Notes: MCE Product type: Recombinant Proteins