BMPR1A/ALK-3, Human (HEK293, His) Preis auf Anfrage
Artikelnummer:
MCE-HY-P75594
Hersteller Artikelnummer:
HY-P75594
Alternativnummer:
MCE-HY-P75594-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Proteine/Peptide
Alternative Synonym:
BMPR1A/ALK-3 Protein, Human (HEK293, His),Human,HEK293
BMPR1A/ALK-3 protein (ACVRLK3) is the receptor bone morphogenetic protein (BMP) type I receptors, widely expressed in tissues[1]. BMPR1A/ALK-3 protein mediates iron metabolism factor hepcidin expression, interacts with GDF5/6 to regulate chondrocyte differentiation and adipogenesis[2][3]. BMPR1A-ID2/ZEB1-TGFBR2 signaling axis could serve as a potentia target for pulmonary arterial hypertension (PAH) and other endothelial-mesenchymal transition (EndoMT)-related vascular disorders[4]. Human BMPR1A/ALK-3 has a full length of 532 a.a., with a motif (107-109 a.a.) mediating specificity for BMP ligand. BMPR1A/ALK-3 Protein, Human (HEK293, His) is produced in HEK293 cells, with a C-terminal His-tags.
Molekulargewicht:
Approximately 28-33 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Formel:
657(Gene_ID)P36894 (Q24-R152)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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