BMPR1A/ALK-3, Human (HEK293, His) Preis auf Anfrage

Catalog Number: MCE-HY-P75594
Article Name: BMPR1A/ALK-3, Human (HEK293, His) Preis auf Anfrage
Biozol Catalog Number: MCE-HY-P75594
Supplier Catalog Number: HY-P75594
Alternative Catalog Number: MCE-HY-P75594-1UNIT
Manufacturer: MedchemExpress
Category: Proteine/Peptide
Alternative Names: BMPR1A/ALK-3 Protein, Human (HEK293, His),Human,HEK293
BMPR1A/ALK-3 protein (ACVRLK3) is the receptor bone morphogenetic protein (BMP) type I receptors, widely expressed in tissues[1]. BMPR1A/ALK-3 protein mediates iron metabolism factor hepcidin expression, interacts with GDF5/6 to regulate chondrocyte differentiation and adipogenesis[2][3]. BMPR1A-ID2/ZEB1-TGFBR2 signaling axis could serve as a potentia target for pulmonary arterial hypertension (PAH) and other endothelial-mesenchymal transition (EndoMT)-related vascular disorders[4]. Human BMPR1A/ALK-3 has a full length of 532 a.a., with a motif (107-109 a.a.) mediating specificity for BMP ligand. BMPR1A/ALK-3 Protein, Human (HEK293, His) is produced in HEK293 cells, with a C-terminal His-tags.
Molecular Weight: Approximately 28-33 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Formula: 657(Gene_ID)P36894 (Q24-R152)(Accession)
Application Notes: MCE Product type: Recombinant Proteins