BMPR1A/ALK-3, Human (HEK293, His) Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-P75594
Supplier Catalog Number:
HY-P75594
Alternative Catalog Number:
MCE-HY-P75594-1UNIT
Manufacturer:
MedchemExpress
Category:
Proteine/Peptide
Alternative Names:
BMPR1A/ALK-3 Protein, Human (HEK293, His),Human,HEK293
BMPR1A/ALK-3 protein (ACVRLK3) is the receptor bone morphogenetic protein (BMP) type I receptors, widely expressed in tissues[1]. BMPR1A/ALK-3 protein mediates iron metabolism factor hepcidin expression, interacts with GDF5/6 to regulate chondrocyte differentiation and adipogenesis[2][3]. BMPR1A-ID2/ZEB1-TGFBR2 signaling axis could serve as a potentia target for pulmonary arterial hypertension (PAH) and other endothelial-mesenchymal transition (EndoMT)-related vascular disorders[4]. Human BMPR1A/ALK-3 has a full length of 532 a.a., with a motif (107-109 a.a.) mediating specificity for BMP ligand. BMPR1A/ALK-3 Protein, Human (HEK293, His) is produced in HEK293 cells, with a C-terminal His-tags.
Molecular Weight:
Approximately 28-33 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Formula:
657(Gene_ID)P36894 (Q24-R152)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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