Iluzanebart is a human monoclonal IgG1 antibody and is the agonist antibody for human TREM2 (hTREM2). Iluzanebart improves the survival and function of microglia by activating the TREM2 signaling pathway to compensate for the loss of CSF1R function. Iluzanebart can be used for research of adult-onset leukoencephalopathy associated with CSF1R (colony stimulating factor 1 receptor) (CSF1R-ALSP)[1].
Molekulargewicht:
(144.92 kDa)
Reinheit:
98.63
CAS Nummer:
[2733621-19-5]
Target-Kategorie:
Ser/Thr Kinase,TREM receptor
Anwendungsbeschreibung:
MCE Product type: Inhibitory Antibodies
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