AMG-966 is a human bispecific antibody (bsAb) targeting TNFSF15/TL1A & TNFalpha. AMG 966 restores the ability of the aglycosylated Fc domain to bind to FcgammaRIa and FcgammaRIIa, leading to the formation of antidrug antibodies (ADA). AMG-966 can be used in Crohns disease and Ulcerative colitis research. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001)[1].
Molekulargewicht:
(145.25 kDa)
Reinheit:
96.19
Target-Kategorie:
TNF Receptor
Anwendungsbeschreibung:
MCE Product type: Inhibitory Antibodies
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