Tesnatilimab (JNJ-64304500) is a human IgG4 monoclonal antibody targeting NKG2D, with a KD value of 9.2 pM[1][2]. Tesnatilimab blocks the binding of ligands to the NKG2D receptor, thereby inhibiting downstream proinflammatory cytokine, cytotoxic mediator signaling pathways and proinflammatory immune responses. Tesnatilimab is applicable to research related to Crohns disease[1][2].
Molekulargewicht:
(143.9 kDa)
Reinheit:
99.80
CAS Nummer:
[2242758-08-1]
Target-Kategorie:
C-type Lectin-like Receptors (CTLRs)
Anwendungsbeschreibung:
MCE Product type: Inhibitory Antibodies
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