Tesnatilimab (JNJ-64304500) is a human IgG4 monoclonal antibody targeting NKG2D, with a KD value of 9.2 pM[1][2]. Tesnatilimab blocks the binding of ligands to the NKG2D receptor, thereby inhibiting downstream proinflammatory cytokine, cytotoxic mediator signaling pathways and proinflammatory immune responses. Tesnatilimab is applicable to research related to Crohns disease[1][2].
Molecular Weight:
(143.9 kDa)
Purity:
99.80
CAS Number:
[2242758-08-1]
Target:
C-type Lectin-like Receptors (CTLRs)
Application Notes:
MCE Product type: Inhibitory Antibodies
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