Astegolimab, CAS [[2173054-79-8]]

Produktübersicht

• Artikelname: Astegolimab, CAS [[2173054-79-8]]
• Artikelnummer: MCE-HY-P99444
• Hersteller Artikelnummer: HY-P99444
• Alternativnummer: MCE-HY-P99444-1MG,MCE-HY-P99444-5MG,MCE-HY-P99444-10MG
• Hersteller: MedchemExpress
• Kategorie: Antikörper
• Alternative Synonym: MSTT 1041A, RG 6149

Produktbeschreibung

Astegolimab (MSTT 1041A, RG 6149) is a human IgG2 monoclonal antibody. Astegolimab blocks IL-33 signaling by targeting the IL-33 receptor ST2. Astegolimab reduces p53 expression, mitigates IL33-upregulated SASP factors such as IL1alpha, IL6 and MCP1. Astegolimab mitigates IL33-increased p-p65/p65 ratio. Astegolimab blocks CM-induced neutrophil extracellular trap (NET) formation. Astegolimab is used in chronic obstructive pulmonary disease (COPD) and myocardial research[1][2][3].

Produkteigenschaften

• Molekulargewicht: (144.98 kDa)
• Reinheit: 99.00
• CAS Nummer: [2173054-79-8]
• Target-Kategorie: Interleukin Related,MDM-2/p53,NF-kappaB

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Inhibitory Antibodies