Astegolimab, CAS [[2173054-79-8]]

Product Overview

• Article Name: Astegolimab, CAS [[2173054-79-8]]
• Biozol Catalog Number: MCE-HY-P99444
• Supplier Catalog Number: HY-P99444
• Alternative Catalog Number: MCE-HY-P99444-1MG,MCE-HY-P99444-5MG,MCE-HY-P99444-10MG
• Manufacturer: MedchemExpress
• Category: Antikörper
• Alternative Names: MSTT 1041A, RG 6149

Product Description

Astegolimab (MSTT 1041A, RG 6149) is a human IgG2 monoclonal antibody. Astegolimab blocks IL-33 signaling by targeting the IL-33 receptor ST2. Astegolimab reduces p53 expression, mitigates IL33-upregulated SASP factors such as IL1alpha, IL6 and MCP1. Astegolimab mitigates IL33-increased p-p65/p65 ratio. Astegolimab blocks CM-induced neutrophil extracellular trap (NET) formation. Astegolimab is used in chronic obstructive pulmonary disease (COPD) and myocardial research[1][2][3].

Product Properties

• Molecular Weight: (144.98 kDa)
• Purity: 99.00
• CAS Number: [2173054-79-8]
• Target: Interleukin Related,MDM-2/p53,NF-kappaB

Application Notes

• Application Notes: MCE Product type: Inhibitory Antibodies