Luspatercept (mIgG2a), CAS [[1373715-00-4]]

Produktübersicht

• Artikelname: Luspatercept (mIgG2a), CAS [[1373715-00-4]]
• Artikelnummer: MCE-HY-P99720A
• Hersteller Artikelnummer: HY-P99720A
• Alternativnummer: MCE-HY-P99720A-1MG,MCE-HY-P99720A-10MG,MCE-HY-P99720A-25MG,MCE-HY-P99720A-5MG,MCE-HY-P99720A-50MG
• Hersteller: MedchemExpress
• Kategorie: Antikörper
• Alternative Synonym: RAP-536

Produktbeschreibung

Luspatercept (mIgG2a) (RAP-536) is a fusion protein, consisting of a modified extracellular domain of human ActRIIB linked to the murine IgG2a Fc domain. Luspatercept (mIgG2a) inhibits Smad2/3 signaling, promotes differentiation of late-stage erythroid precursors and mitigates ineffective erythropoiesis (IE) in murine beta-thalassemia. Luspatercept (mIgG2a) reduces anemia, alpha-globin aggregates, hemolysis, and disease complications of IE such as iron overload, splenomegaly, and bone defects[1].

Produkteigenschaften

• Molekulargewicht: (75.709 kDa)
• Reinheit: 99.78
• CAS Nummer: [1373715-00-4]
• Target-Kategorie: TGF-beta/Smad

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Inhibitory Antibodies