Luspatercept (mIgG2a), CAS [[1373715-00-4]]

Product Overview

• Article Name: Luspatercept (mIgG2a), CAS [[1373715-00-4]]
• Biozol Catalog Number: MCE-HY-P99720A
• Supplier Catalog Number: HY-P99720A
• Alternative Catalog Number: MCE-HY-P99720A-1MG,MCE-HY-P99720A-10MG,MCE-HY-P99720A-25MG,MCE-HY-P99720A-5MG,MCE-HY-P99720A-50MG
• Manufacturer: MedchemExpress
• Category: Antikörper
• Alternative Names: RAP-536

Product Description

Luspatercept (mIgG2a) (RAP-536) is a fusion protein, consisting of a modified extracellular domain of human ActRIIB linked to the murine IgG2a Fc domain. Luspatercept (mIgG2a) inhibits Smad2/3 signaling, promotes differentiation of late-stage erythroid precursors and mitigates ineffective erythropoiesis (IE) in murine beta-thalassemia. Luspatercept (mIgG2a) reduces anemia, alpha-globin aggregates, hemolysis, and disease complications of IE such as iron overload, splenomegaly, and bone defects[1].

Product Properties

• Molecular Weight: (75.709 kDa)
• Purity: 99.78
• CAS Number: [1373715-00-4]
• Target: TGF-beta/Smad

Application Notes

• Application Notes: MCE Product type: Inhibitory Antibodies