Amivantamab (FUT8-KO)

Produktübersicht

• Artikelname: Amivantamab (FUT8-KO)
• Artikelnummer: MCE-HY-P9977A
• Hersteller Artikelnummer: HY-P9977A
• Alternativnummer: MCE-HY-P9977A-10MG,MCE-HY-P9977A-1MG,MCE-HY-P9977A-5MG
• Hersteller: MedchemExpress
• Kategorie: Antikörper

Produktbeschreibung

Amivantamab (FUT8-KO) is an anti-EGFR-MET monoclonal antibody expressed by CHO cells with the fucosyltransferase 8 gene (FUT8) knocked out. Fucose deficiency enhances the ADCC effect of the antibody. Amivantamab (FUT8-KO) inhibits ligand binding, promotes endocytosis and degradation of receptor-antibody complexes, and induces Fc-dependent cytokinesis in macrophages and antibody-dependent cytotoxicity in natural killer cells[1].

Produkteigenschaften

• Molekulargewicht: (145.88 kDa)
• Reinheit: 98
• Target-Kategorie: EGFR

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Inhibitory Antibodies