Amivantamab (FUT8-KO)

Product Overview

• Article Name: Amivantamab (FUT8-KO)
• Biozol Catalog Number: MCE-HY-P9977A
• Supplier Catalog Number: HY-P9977A
• Alternative Catalog Number: MCE-HY-P9977A-10MG,MCE-HY-P9977A-1MG,MCE-HY-P9977A-5MG
• Manufacturer: MedchemExpress
• Category: Antikörper

Product Description

Amivantamab (FUT8-KO) is an anti-EGFR-MET monoclonal antibody expressed by CHO cells with the fucosyltransferase 8 gene (FUT8) knocked out. Fucose deficiency enhances the ADCC effect of the antibody. Amivantamab (FUT8-KO) inhibits ligand binding, promotes endocytosis and degradation of receptor-antibody complexes, and induces Fc-dependent cytokinesis in macrophages and antibody-dependent cytotoxicity in natural killer cells[1].

Product Properties

• Molecular Weight: (145.88 kDa)
• Purity: 98
• Target: EGFR

Application Notes

• Application Notes: MCE Product type: Inhibitory Antibodies