Cofetuzumab pelidotin, CAS [[1869937-48-3]]

Produktübersicht

• Artikelname: Cofetuzumab pelidotin, CAS [[1869937-48-3]]
• Artikelnummer: MCE-HY-P99829
• Hersteller Artikelnummer: HY-P99829
• Alternativnummer: MCE-HY-P99829-10MG,MCE-HY-P99829-5MG,MCE-HY-P99829-1MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: PF-06647020, ABBV-647, h6M24-vc0101

Produktbeschreibung

Cofetuzumab pelidotin (PF-06647020) is a PTK7-targeting ADC comprising a humanized anti-PTK7 mAb (hu6M024, IgG1) joined to an auristatin microtubule inhibitor payload, auristatin-0101 (Aur0101, HY-12522), by a cleavable valine-citrulline (vc)-based linker. Cofetuzumab pelidotin has a DAR of 4. Cofetuzumab pelidotin binds to cell-surface PTK7 with an EC50 of 1153 pM by flow cytometry. Cofetuzumab pelidotin has the potential for solid tumors research[1][2][3].

Produkteigenschaften

• Molekulargewicht: 151784 (average)
• Reinheit: 99.67
• CAS Nummer: [1869937-48-3]
• Target-Kategorie: Antibody-Drug Conjugates (ADCs),Microtubule/Tubulin

Anwendungsbeschreibung

• Anwendungsbeschreibung: ADC Related