Cofetuzumab pelidotin, CAS [[1869937-48-3]]

Product Overview

• Article Name: Cofetuzumab pelidotin, CAS [[1869937-48-3]]
• Biozol Catalog Number: MCE-HY-P99829
• Supplier Catalog Number: HY-P99829
• Alternative Catalog Number: MCE-HY-P99829-10MG,MCE-HY-P99829-5MG,MCE-HY-P99829-1MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: PF-06647020, ABBV-647, h6M24-vc0101

Product Description

Cofetuzumab pelidotin (PF-06647020) is a PTK7-targeting ADC comprising a humanized anti-PTK7 mAb (hu6M024, IgG1) joined to an auristatin microtubule inhibitor payload, auristatin-0101 (Aur0101, HY-12522), by a cleavable valine-citrulline (vc)-based linker. Cofetuzumab pelidotin has a DAR of 4. Cofetuzumab pelidotin binds to cell-surface PTK7 with an EC50 of 1153 pM by flow cytometry. Cofetuzumab pelidotin has the potential for solid tumors research[1][2][3].

Product Properties

• Molecular Weight: 151784 (average)
• Purity: 99.67
• CAS Number: [1869937-48-3]
• Target: Antibody-Drug Conjugates (ADCs),Microtubule/Tubulin

Application Notes

• Application Notes: ADC Related