4-Hydroxyestrone, CAS [[3131-23-5]]

Produktübersicht

• Artikelname: 4-Hydroxyestrone, CAS [[3131-23-5]]
• Artikelnummer: MCE-HY-W009300
• Hersteller Artikelnummer: HY-W009300
• Alternativnummer: MCE-HY-W009300-5MG,MCE-HY-W009300-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: 4-OHE1

Produktbeschreibung

4-Hydroxyestrone (4-OHE1) is a brain-penetrant estrogen metabolite. 4-Hydroxyestrone shows neuroprotective effects involving increased cytoplasmic localization of p53 resulting from SIRT1-mediated p53 deacetylation. 4-Hydroxyestrone relies on PDI to mediate its protective effect against chemically induced ferroptosis in estrogen receptor-negative cancer cells. 4-Hydroxyestrone inhibits lipid peroxidation and lipid-ROS accumulation. 4-Hydroxyestrone blocks preovulatory luteinizing hormone surges in Rattus norvegicus. 4-Hydroxyestrone can be used for the researches of neurodegeneration, breast cancer and endocrine disease[1][2][3].

Produkteigenschaften

• Molekulargewicht: 286.37
• Reinheit: 99
• CAS Nummer: [3131-23-5]
• Formel: C18H22O3
• Target-Kategorie: Endogenous Metabolite,Estrogen Receptor/ERR,Ferroptosis,MDM-2/p53,PDI,Reactive Oxygen Species (ROS),Sirtuin

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Natural Products