4-Hydroxyestrone, CAS [[3131-23-5]]

Product Overview

• Article Name: 4-Hydroxyestrone, CAS [[3131-23-5]]
• Biozol Catalog Number: MCE-HY-W009300
• Supplier Catalog Number: HY-W009300
• Alternative Catalog Number: MCE-HY-W009300-5MG,MCE-HY-W009300-10MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: 4-OHE1

Product Description

4-Hydroxyestrone (4-OHE1) is a brain-penetrant estrogen metabolite. 4-Hydroxyestrone shows neuroprotective effects involving increased cytoplasmic localization of p53 resulting from SIRT1-mediated p53 deacetylation. 4-Hydroxyestrone relies on PDI to mediate its protective effect against chemically induced ferroptosis in estrogen receptor-negative cancer cells. 4-Hydroxyestrone inhibits lipid peroxidation and lipid-ROS accumulation. 4-Hydroxyestrone blocks preovulatory luteinizing hormone surges in Rattus norvegicus. 4-Hydroxyestrone can be used for the researches of neurodegeneration, breast cancer and endocrine disease[1][2][3].

Product Properties

• Molecular Weight: 286.37
• Purity: 99
• CAS Number: [3131-23-5]
• Formula: C18H22O3
• Target: Endogenous Metabolite,Estrogen Receptor/ERR,Ferroptosis,MDM-2/p53,PDI,Reactive Oxygen Species (ROS),Sirtuin

Application Notes

• Application Notes: MCE Product type: Natural Products