Citronellol (()-Citronellol) is an orally active inducer of apoptosis. Citronellol can prevent oxidative stress, mitochondrial dysfunction, and apoptosis in the SH-SY5Y cell Parkinsons disease model induced by 6-OHDA by regulating the ROS-NO, MAPK/ERK, and PI3K/Akt signaling pathways. Citronellol can induce necroptosis in human lung cancer cells through the TNF-alpha pathway and accumulation of ROS. Citronellol can reduce the levels of LC-3 and p62 to regulate the autophagy pathway, inhibit oxidative stress and neuroinflammation, and thus have neuroprotective effects on Parkinsons rats. Citronellol exhibits anti-fungal activity against Trichophyton rubrum by inhibiting ergosterol synthesis[2][4][6][7].
Molekulargewicht:
156.27
Reinheit:
98.78
CAS Nummer:
[106-22-9]
Formel:
C10H20O
Target-Kategorie:
Apoptosis,Atg8/LC3,Autophagy,ERK,Fungal,Necroptosis,p62,PI3K,Reactive Oxygen Species (ROS),TNF Receptor
Anwendungsbeschreibung:
MCE Product type: Natural Products
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
