Meso-tetraphenylchlorin, CAS [[2669-65-0]] Preis auf Anfrage
Artikelnummer:
MCE-HY-W010713
Hersteller Artikelnummer:
HY-W010713
Alternativnummer:
MCE-HY-W010713-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Alternative Synonym:
Fimaporfin (free base)
Meso-tetraphenylchlorin (TPCS2a) is a photosensitizer with poor water solubility, which limits its use in the blood circulation. However, TPCS2a NPs nanoparticles can be prepared based on polylactic-co-polyethylene glycol acid (PLGA) polymer core loaded with TPCS2. Such nanoparticles can be coated with mesenchymal stem cell-derived plasma membranes (mMSCs) to form mMSC-TPCS2a NPs, which prolongs blood circulation time and improves tumor targeting ability. Compared with uncoated TPCS2a NPs, mMSC-TPCS2a NPs can reduce macrophage uptake by 54% to 70% under different conditions. Both nanoparticle forms are effectively accumulated in MCF7 and MDA-MB-231 breast cancer cells, while uptake in normal breast epithelial cells MCF10A is significantly lower[1].
Molekulargewicht:
618.77
CAS Nummer:
[2669-65-0]
Formel:
C44H34N4
Target-Kategorie:
Photosensitizer
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten