Meso-tetraphenylchlorin, CAS [[2669-65-0]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-W010713
Supplier Catalog Number:
HY-W010713
Alternative Catalog Number:
MCE-HY-W010713-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
Fimaporfin (free base)
Meso-tetraphenylchlorin (TPCS2a) is a photosensitizer with poor water solubility, which limits its use in the blood circulation. However, TPCS2a NPs nanoparticles can be prepared based on polylactic-co-polyethylene glycol acid (PLGA) polymer core loaded with TPCS2. Such nanoparticles can be coated with mesenchymal stem cell-derived plasma membranes (mMSCs) to form mMSC-TPCS2a NPs, which prolongs blood circulation time and improves tumor targeting ability. Compared with uncoated TPCS2a NPs, mMSC-TPCS2a NPs can reduce macrophage uptake by 54% to 70% under different conditions. Both nanoparticle forms are effectively accumulated in MCF7 and MDA-MB-231 breast cancer cells, while uptake in normal breast epithelial cells MCF10A is significantly lower[1].
Molecular Weight:
618.77
CAS Number:
[2669-65-0]
Formula:
C44H34N4
Target:
Photosensitizer
Application Notes:
MCE Product type: Reference compound
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