4-Methyl-2-oxopentanoic acid, CAS [[816-66-0]]

Artikelnummer: MCE-HY-W012722
Artikelname: 4-Methyl-2-oxopentanoic acid, CAS [[816-66-0]]
Artikelnummer: MCE-HY-W012722
Hersteller Artikelnummer: HY-W012722
Alternativnummer: MCE-HY-W012722-10MMX1ML,MCE-HY-W012722-1G,MCE-HY-W012722-100MG,MCE-HY-W012722-500MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
Alternative Synonym: alpha-Ketoisocaproic acid
4-Methyl-2-oxopentanoic acid (alpha-Ketoisocaproic acid) is a metabolite of L-leucine and is involved in energy metabolism. 4-Methyl-2-oxopentanoic acid increases endoplasmic reticulum stress, promotes lipid accumulation in preadipocytes and insulin resistance by impairing mTOR and autophagy signaling pathways. 4-Methyl-2-oxopentanoic acid also causes oxidative damage, leading to cognitive deficits, inhibits alpha-ketoglutarate dehydrogenase activity, acts as an oxidative phosphorylation uncoupler and metabolic inhibitor. 4-Methyl-2-oxopentanoic acid acts as a nutrient signal and stimulates skeletal muscle protein synthesis. 4-Methyl-2-oxopentanoic acid can be used in the study of maple syrup urine disease[1][2][3][4][5].
Molekulargewicht: 130.14
Reinheit: 99.51
CAS Nummer: [816-66-0]
Formel: C6H10O3
Target-Kategorie: Autophagy,Endogenous Metabolite,mTOR,SOD
Anwendungsbeschreibung: MCE Product type: Natural Products