Alpidem-d14, CAS [[1189962-23-9]] Preis auf Anfrage
Artikelnummer:
MCE-HY-W013150S
Hersteller Artikelnummer:
HY-W013150S
Alternativnummer:
MCE-HY-W013150S-10MG,MCE-HY-W013150S-1MG
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Alpidem-d14 is the deuterium labeled Alpidem (HY-W013150)[1]. Alpidem, an anxiolytic agent, is an orally active and brain-penetrant GABAA receptor ligand, binds to alpha1beta2gamma2 subunit-containing GABAA receptors (IC50 of 17 nM) over alpha5beta2gamma2 subunit-containing GABAA receptors (IC50 of >10 µM). Alpidem modulates calcium-induced mitochondrial permeability transition, induces glutathione depletion and hepatocyte necrosis, potentiates TNF-alpha toxicity, inhibits marble-burying and locomotor activity, enhances stressed rodent feeding behavior, and exerts anticonvulsant effects. Alpidem can be used for the research of anxiety, anxiety disorders, and convulsions.
Molekulargewicht:
418.42
CAS Nummer:
[1189962-23-9]
Formel:
C21H9D14Cl2N3O
Target-Kategorie:
GABA Receptor,Isotope-Labeled Compounds
Anwendungsbeschreibung:
MCE Product type: Isotope-Labeled Compounds
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
