Alpidem-d14, CAS [[1189962-23-9]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-W013150S
Supplier Catalog Number:
HY-W013150S
Alternative Catalog Number:
MCE-HY-W013150S-10MG,MCE-HY-W013150S-1MG
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alpidem-d14 is the deuterium labeled Alpidem (HY-W013150)[1]. Alpidem, an anxiolytic agent, is an orally active and brain-penetrant GABAA receptor ligand, binds to alpha1beta2gamma2 subunit-containing GABAA receptors (IC50 of 17 nM) over alpha5beta2gamma2 subunit-containing GABAA receptors (IC50 of >10 µM). Alpidem modulates calcium-induced mitochondrial permeability transition, induces glutathione depletion and hepatocyte necrosis, potentiates TNF-alpha toxicity, inhibits marble-burying and locomotor activity, enhances stressed rodent feeding behavior, and exerts anticonvulsant effects. Alpidem can be used for the research of anxiety, anxiety disorders, and convulsions.
Molecular Weight:
418.42
CAS Number:
[1189962-23-9]
Formula:
C21H9D14Cl2N3O
Target:
GABA Receptor,Isotope-Labeled Compounds
Application Notes:
MCE Product type: Isotope-Labeled Compounds
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