Rizatriptan, CAS [[144034-80-0]] Preis auf Anfrage

Produktübersicht

• Artikelname: Rizatriptan, CAS [[144034-80-0]] Preis auf Anfrage
• Artikelnummer: MCE-HY-W018475
• Hersteller Artikelnummer: HY-W018475
• Alternativnummer: MCE-HY-W018475-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: MK 462 (free base)

Produktbeschreibung

Rizatriptan (MK 462 free base) is an orally active 5-HT1B/5-HT1D receptor agonist, with BBB permeability. Rizatriptan exerts significant anti-migraine effects by constricting intracranial and extracranial blood vessels and inhibiting neuropeptide release. Rizatriptan exhibits species- and tissue-specific metabolic characteristics, for example, it undergoes oxidative deamination mainly by MAO-A in the liver of brown rats, so co-administration with MAO-A inhibitors is prohibited. Rizatriptan may also exacerbate nitroglycerin-induced cutaneous allodynia, prolong the duration of central sensitization, and increase anxiety-like behavior and active drug-seeking behavior in mice. Rizatriptan has been widely used in studies related to migraine and medication-overuse headache[1][2].

Produkteigenschaften

• Molekulargewicht: 269.34
• CAS Nummer: [144034-80-0]
• Formel: C15H19N5
• Target-Kategorie: 5-HT Receptor

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound