HDGFRP2/PSIP1-IN-1, CAS [[166196-54-9]]

Produktübersicht

• Artikelname: HDGFRP2/PSIP1-IN-1, CAS [[166196-54-9]]
• Artikelnummer: MCE-HY-W023758
• Hersteller Artikelnummer: HY-W023758
• Alternativnummer: MCE-HY-W023758-5G,MCE-HY-W023758-25G,MCE-HY-W023758-1G,MCE-HY-W023758-10MMX1ML,MCE-HY-W023758-10G
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: 4-(4-Bromo-1H-pyrazol-5-yl)pyridine

Produktbeschreibung

HDGFRP2/PSIP1-IN-1 (compound BPP) is a dual inhibitor targeting the PWWP domain of hepatocarcinogenic growth factor-related protein 2 (HDGFRP2) and its homologous protein PSIP1, hinder the development and progression of diffuse intrinsic pontine glioma (DIPG). HDGFRP2/PSIP1-IN-1 binds to HDGFRP2 with a Kd value of 7 µM and a ligand efficiency of 0.47, it binds to the PSIP1 PWWP domain with a Kd value of 27 µM, meanwhile, it has a Kd value of 14 µM for HDGFRP3, indicating its effectiveness as an inhibitor of the HDGFRP2 PWWP subfamily[1].

Produkteigenschaften

• Molekulargewicht: 224.06
• Reinheit: 99.50
• CAS Nummer: [166196-54-9]
• Formel: C8H6BrN3
• Target-Kategorie: DNA/RNA Synthesis

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound