HDGFRP2/PSIP1-IN-1, CAS [[166196-54-9]]

Product Overview

• Article Name: HDGFRP2/PSIP1-IN-1, CAS [[166196-54-9]]
• Biozol Catalog Number: MCE-HY-W023758
• Supplier Catalog Number: HY-W023758
• Alternative Catalog Number: MCE-HY-W023758-5G,MCE-HY-W023758-25G,MCE-HY-W023758-1G,MCE-HY-W023758-10MMX1ML,MCE-HY-W023758-10G
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: 4-(4-Bromo-1H-pyrazol-5-yl)pyridine

Product Description

HDGFRP2/PSIP1-IN-1 (compound BPP) is a dual inhibitor targeting the PWWP domain of hepatocarcinogenic growth factor-related protein 2 (HDGFRP2) and its homologous protein PSIP1, hinder the development and progression of diffuse intrinsic pontine glioma (DIPG). HDGFRP2/PSIP1-IN-1 binds to HDGFRP2 with a Kd value of 7 µM and a ligand efficiency of 0.47, it binds to the PSIP1 PWWP domain with a Kd value of 27 µM, meanwhile, it has a Kd value of 14 µM for HDGFRP3, indicating its effectiveness as an inhibitor of the HDGFRP2 PWWP subfamily[1].

Product Properties

• Molecular Weight: 224.06
• Purity: 99.50
• CAS Number: [166196-54-9]
• Formula: C8H6BrN3
• Target: DNA/RNA Synthesis

Application Notes

• Application Notes: MCE Product type: Reference compound