5-Nitro-1H-indazole-3-carbonitrile, CAS [[90348-29-1]] Preis auf Anfrage

Produktübersicht

• Artikelname: 5-Nitro-1H-indazole-3-carbonitrile, CAS [[90348-29-1]] Preis auf Anfrage
• Artikelnummer: MCE-HY-W047432
• Hersteller Artikelnummer: HY-W047432
• Alternativnummer: MCE-HY-W047432-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: DL0805

Produktbeschreibung

5-Nitro-1H-indazole-3-carbonitrile (DL0805) is a Rho kinase(ROCK) inhibitor with an IC50 of 6.67 µM for ROCK-I. 5-Nitro-1H-indazole-3-carbonitrile reduces Norepinephrine (HY-13715)-induced transient contraction and inhibits contraction induced by increasing external calcium in the endothelium-denuded rings of rat models. 5-Nitro-1H-indazole-3-carbonitrile has a vasorelaxant activity but high toxicity. 5-Nitro-1H-indazole-3-carbonitrile can be used for cardiovascular diseases, especially hypertension research[1][2].

Produkteigenschaften

• Molekulargewicht: 188.14
• CAS Nummer: [90348-29-1]
• Formel: C8H4N4O2
• Target-Kategorie: ROCK

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound