5-Nitro-1H-indazole-3-carbonitrile, CAS [[90348-29-1]] Preis auf Anfrage

Product Overview

• Article Name: 5-Nitro-1H-indazole-3-carbonitrile, CAS [[90348-29-1]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-W047432
• Supplier Catalog Number: HY-W047432
• Alternative Catalog Number: MCE-HY-W047432-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: DL0805

Product Description

5-Nitro-1H-indazole-3-carbonitrile (DL0805) is a Rho kinase(ROCK) inhibitor with an IC50 of 6.67 µM for ROCK-I. 5-Nitro-1H-indazole-3-carbonitrile reduces Norepinephrine (HY-13715)-induced transient contraction and inhibits contraction induced by increasing external calcium in the endothelium-denuded rings of rat models. 5-Nitro-1H-indazole-3-carbonitrile has a vasorelaxant activity but high toxicity. 5-Nitro-1H-indazole-3-carbonitrile can be used for cardiovascular diseases, especially hypertension research[1][2].

Product Properties

• Molecular Weight: 188.14
• CAS Number: [90348-29-1]
• Formula: C8H4N4O2
• Target: ROCK

Application Notes

• Application Notes: MCE Product type: Reference compound