Ca2+ -Langerin-IN-1, CAS [[79932-56-2]] Preis auf Anfrage

Produktübersicht

• Artikelname: Ca2+ -Langerin-IN-1, CAS [[79932-56-2]] Preis auf Anfrage
• Artikelnummer: MCE-HY-W069974
• Hersteller Artikelnummer: HY-W069974
• Alternativnummer: MCE-HY-W069974-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

Ca2+-Langerin-IN-1 (Compound 3) is a allosteric Langerin inhibitor. Langerin is a C-type lectin that is expressed on Langerhans cells and plays a crucial role in pathogen recognition and innate immune activation. The KD value of the CRD domain of murine Langerin protein for Ca2+-Langerin-IN-1 is 17 µM under the presence of Ca and 53 µM under the absence of Ca competition. Ca2+-Langerin-IN-1 induces conformational changes and competitively replaces Ca, thereby inhibiting the carbohydrate recognition function of the protein. Ca2+-Langerin-IN-1 can be used in the research of immunomodulatory therapy[1].

Produkteigenschaften

• Molekulargewicht: 224.24
• CAS Nummer: [79932-56-2]
• Formel: C9H8N2O3S
• Target-Kategorie: Calcium Channel

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound