Ca2+ -Langerin-IN-1, CAS [[79932-56-2]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-W069974
Supplier Catalog Number:
HY-W069974
Alternative Catalog Number:
MCE-HY-W069974-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Ca2+-Langerin-IN-1 (Compound 3) is a allosteric Langerin inhibitor. Langerin is a C-type lectin that is expressed on Langerhans cells and plays a crucial role in pathogen recognition and innate immune activation. The KD value of the CRD domain of murine Langerin protein for Ca2+-Langerin-IN-1 is 17 µM under the presence of Ca and 53 µM under the absence of Ca competition. Ca2+-Langerin-IN-1 induces conformational changes and competitively replaces Ca, thereby inhibiting the carbohydrate recognition function of the protein. Ca2+-Langerin-IN-1 can be used in the research of immunomodulatory therapy[1].
Molecular Weight:
224.24
CAS Number:
[79932-56-2]
Formula:
C9H8N2O3S
Target:
Calcium Channel
Application Notes:
MCE Product type: Reference compound
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