Perfluorotetradecanoic acid, CAS [[376-06-7]] Preis auf Anfrage

Produktübersicht

• Artikelname: Perfluorotetradecanoic acid, CAS [[376-06-7]] Preis auf Anfrage
• Artikelnummer: MCE-HY-W073128
• Hersteller Artikelnummer: HY-W073128
• Alternativnummer: MCE-HY-W073128-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: PFTeDA

Produktbeschreibung

Perfluorotetradecanoic acid (PFTeDA) is an orally active perfluoroalkyl substance. Perfluorotetradecanoic acid directly binds to the ligand-binding domain of purified hPPARgamma, with a Kd value of 157.8 µM. Perfluorotetradecanoic acid significantly reduces the activity of the SIRT1/PGC1alpha and AMPK signaling pathways while stimulating the activity of the AKT1/mTOR signaling pathway. Perfluorotetradecanoic acid significantly upregulates the expression of corticosterone biosynthesis genes. Perfluorotetradecanoic acid increases ROS levels and promotes Apoptosis. Perfluorotetradecanoic acid impairs Leydig cell function and male reproductive endocrine function in adult male rats[1][3][2].

Produkteigenschaften

• Molekulargewicht: 714.11
• Reinheit: 98
• CAS Nummer: [376-06-7]
• Formel: C14HF27O2
• Target-Kategorie: Akt,AMPK,Apoptosis,mTOR,PGC-1alpha,PPAR,Reactive Oxygen Species (ROS)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1