Perfluorotetradecanoic acid, CAS [[376-06-7]] Preis auf Anfrage

Product Overview

• Article Name: Perfluorotetradecanoic acid, CAS [[376-06-7]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-W073128
• Supplier Catalog Number: HY-W073128
• Alternative Catalog Number: MCE-HY-W073128-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: PFTeDA

Product Description

Perfluorotetradecanoic acid (PFTeDA) is an orally active perfluoroalkyl substance. Perfluorotetradecanoic acid directly binds to the ligand-binding domain of purified hPPARgamma, with a Kd value of 157.8 µM. Perfluorotetradecanoic acid significantly reduces the activity of the SIRT1/PGC1alpha and AMPK signaling pathways while stimulating the activity of the AKT1/mTOR signaling pathway. Perfluorotetradecanoic acid significantly upregulates the expression of corticosterone biosynthesis genes. Perfluorotetradecanoic acid increases ROS levels and promotes Apoptosis. Perfluorotetradecanoic acid impairs Leydig cell function and male reproductive endocrine function in adult male rats[1][3][2].

Product Properties

• Molecular Weight: 714.11
• Purity: 98
• CAS Number: [376-06-7]
• Formula: C14HF27O2
• Target: Akt,AMPK,Apoptosis,mTOR,PGC-1alpha,PPAR,Reactive Oxygen Species (ROS)

Application Notes

• Application Notes: MCE Product type: Reference compound1