Perfluorotetradecanoic acid (PFTeDA) is a PPARgamma inhibitor. Perfluorotetradecanoic acid binds to human PPARgamma ligand binding domain with IC50 of 22.8 µM, Kd of 157.8 µM. Perfluorotetradecanoic acid inhibits the function of Leydig cells by inducing oxidative stress and apoptosis. Perfluorotetradecanoic acid stimulates corticosterone biosynthesis but inhibits aldosterone production[1][2][3].
Molecular Weight:
714.11
Purity:
98
CAS Number:
[376-06-7]
Formula:
C14HF27O2
Target:
Apoptosis,PPAR
Application Notes:
MCE Product type: Reference compound
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