Thalidomide 5-fluoride, CAS [[835616-61-0]]

Produktübersicht

• Artikelname: Thalidomide 5-fluoride, CAS [[835616-61-0]]
• Artikelnummer: MCE-HY-W087383
• Hersteller Artikelnummer: HY-W087383
• Alternativnummer: MCE-HY-W087383-1G,MCE-HY-W087383-5G,MCE-HY-W087383-10G,MCE-HY-W087383-25G,MCE-HY-W087383-10MMX1ML
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

Thalidomide 5-fluoride is a thalidomide-based Cereblon ligand used to recruit Cereblon protein. Thalidomide 5-fluoride can be linked to target protein ligands (e.g. IRAK4) through a linker to form PROTAC molecules (e.g. PROTAC IRAK4 degrader-1). PROTAC IRAK4 degrader-1 caused 20-50%, and >50% IRAK4 protein degradation in OCI-LY-10 cells at concentrations of 0.01, 0.1, and 1 µM, respectively[1][2].

Produkteigenschaften

• Molekulargewicht: 276.22
• Reinheit: 99.96
• CAS Nummer: [835616-61-0]
• Formel: C13H9FN2O4
• Target-Kategorie: Apoptosis,Autophagy,Ligands for E3 Ligase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound