2-Guanidinobezimidazole, CAS [[5418-95-1]]

Produktübersicht

• Artikelname: 2-Guanidinobezimidazole, CAS [[5418-95-1]]
• Artikelnummer: MCE-HY-W158030
• Hersteller Artikelnummer: HY-W158030
• Alternativnummer: MCE-HY-W158030-250MG,MCE-HY-W158030-1G,MCE-HY-W158030-500MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: 2GBI

Produktbeschreibung

2-Guanidinobezimidazole (2GBI) is a selective agonist of NLRP3, with a KD value of 1.29 µM to His-GFP-NLRP3. 2-Guanidinobezimidazole binds directly to the LRR domain of NLRP3, promoting inflammasome assembly and activation. 2-Guanidinobezimidazole promotes anti-tumor immunity, inhibits tumor growth, and overcome immune checkpoint blockade (ICB) resistance[1].

Produkteigenschaften

• Molekulargewicht: 175.19
• Reinheit: 95.74
• CAS Nummer: [5418-95-1]
• Formel: C8H9N5
• Target-Kategorie: NOD-like Receptor (NLR)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound2