2-Guanidinobezimidazole, CAS [[5418-95-1]]

Product Overview

• Article Name: 2-Guanidinobezimidazole, CAS [[5418-95-1]]
• Biozol Catalog Number: MCE-HY-W158030
• Supplier Catalog Number: HY-W158030
• Alternative Catalog Number: MCE-HY-W158030-500MG,MCE-HY-W158030-250MG,MCE-HY-W158030-1G
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: 2GBI

Product Description

2-Guanidinobezimidazole (2GBI) is a NLRP3 agonist with a KD of 1.29 µM and a selective state-dependent HVCN1 blocker. 2-Guanidinobezimidazole directly binds NLRP3s LRR domain, enhances NLRP3-ASC and NLRP3-NEK7 interactions, and drives NLRP3 inflammasome activation. 2-Guanidinobezimidazole can be used for the research of LLC lung carcinoma, B16F10 melanoma and ischemic stroke[1][2].

Product Properties

• Molecular Weight: 175.19
• Purity: 95.74
• CAS Number: [5418-95-1]
• Formula: C8H9N5
• Target: NOD-like Receptor (NLR),Vasopressin Receptor

Application Notes

• Application Notes: MCE Product type: Reference compound