2-Guanidinobezimidazole, CAS [[5418-95-1]]

Product Overview

• Article Name: 2-Guanidinobezimidazole, CAS [[5418-95-1]]
• Biozol Catalog Number: MCE-HY-W158030
• Supplier Catalog Number: HY-W158030
• Alternative Catalog Number: MCE-HY-W158030-250MG,MCE-HY-W158030-1G,MCE-HY-W158030-500MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: 2GBI

Product Description

2-Guanidinobezimidazole (2GBI) is a selective agonist of NLRP3, with a KD value of 1.29 µM to His-GFP-NLRP3. 2-Guanidinobezimidazole binds directly to the LRR domain of NLRP3, promoting inflammasome assembly and activation. 2-Guanidinobezimidazole promotes anti-tumor immunity, inhibits tumor growth, and overcome immune checkpoint blockade (ICB) resistance[1].

Product Properties

• Molecular Weight: 175.19
• Purity: 95.74
• CAS Number: [5418-95-1]
• Formula: C8H9N5
• Target: NOD-like Receptor (NLR)

Application Notes

• Application Notes: MCE Product type: Reference compound2