MASM7 is a mitofusin activator, and can achieve mitochondrial fusion via mitofusins. MASM7 can increase Mito AR with an EC50 value of 75 nM in MEFs in concentration-responsively, and can promote mitochondrial fusion by directly activating MFN2 or MFN. MASM7 also demonstrates direct binding to the HR2 domain of MFN2 with Kd value of 1.1 µM[1].
Molekulargewicht:
453.58
Reinheit:
99.85
CAS Nummer:
[920868-45-7]
Formel:
C22H23N5O2S2
Target-Kategorie:
Mitochondrial Metabolism
Anwendungsbeschreibung:
MCE Product type: Reference compound
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