MASM7 is a mitofusin activator, and can achieve mitochondrial fusion via mitofusins. MASM7 can increase Mito AR with an EC50 value of 75 nM in MEFs in concentration-responsively, and can promote mitochondrial fusion by directly activating MFN2 or MFN. MASM7 also demonstrates direct binding to the HR2 domain of MFN2 with Kd value of 1.1 µM[1].
Molecular Weight:
453.58
Purity:
99.85
CAS Number:
[920868-45-7]
Formula:
C22H23N5O2S2
Target:
Mitochondrial Metabolism
Application Notes:
MCE Product type: Reference compound
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