Estradiol 17-(beta-D-Glucuronide), CAS [[1806-98-0]]
Artikelnummer:
MCE-HY-W353102
Hersteller Artikelnummer:
HY-W353102
Alternativnummer:
MCE-HY-W353102-1MG
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Estradiol 17-(beta-D-Glucuronide) is a D-ring glucuronide metabolite of natural estrogen formed in the liver. Estradiol 17-(beta-D-Glucuronide) is a substrate of the organic anion-transporting polypeptide family (Oatp) and multidrug resistance-associated protein 2 (Mrp2). Estradiol 17-(beta-D-Glucuronide) regulates MRP8-mediated transport processes and inhibits MRP8-mediated transport of dehydroepiandrosterone 3-sulfate and taurocholic acid. Estradiol 17-(beta-D-Glucuronide) induces immediate, reversible reduction of bile flow and acute intrahepatic cholestasis in female rats without altering the bile acid composition in bile. Estradiol 17-(beta-D-Glucuronide) can be used in studies related to intrahepatic cholestasis[1][2][3].
Molekulargewicht:
448.51
Reinheit:
99
CAS Nummer:
[1806-98-0]
Formel:
C24H32O8
Target-Kategorie:
Endogenous Metabolite,P-glycoprotein
Anwendungsbeschreibung:
MCE Product type: Reference compound
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