Estradiol 17-(beta-D-Glucuronide), CAS [[1806-98-0]]

Product Overview

• Article Name: Estradiol 17-(beta-D-Glucuronide), CAS [[1806-98-0]]
• Biozol Catalog Number: MCE-HY-W353102
• Supplier Catalog Number: HY-W353102
• Alternative Catalog Number: MCE-HY-W353102-1MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

Estradiol 17-(beta-D-Glucuronide) is a D-ring glucuronide metabolite of natural estrogen formed in the liver. Estradiol 17-(beta-D-Glucuronide) is a substrate of the organic anion-transporting polypeptide family (Oatp) and multidrug resistance-associated protein 2 (Mrp2). Estradiol 17-(beta-D-Glucuronide) regulates MRP8-mediated transport processes and inhibits MRP8-mediated transport of dehydroepiandrosterone 3-sulfate and taurocholic acid. Estradiol 17-(beta-D-Glucuronide) induces immediate, reversible reduction of bile flow and acute intrahepatic cholestasis in female rats without altering the bile acid composition in bile. Estradiol 17-(beta-D-Glucuronide) can be used in studies related to intrahepatic cholestasis[1][2][3].

Product Properties

• Molecular Weight: 448.51
• Purity: 99
• CAS Number: [1806-98-0]
• Formula: C24H32O8
• Target: Endogenous Metabolite,P-glycoprotein

Application Notes

• Application Notes: MCE Product type: Reference compound