C1s-IN-1 trihydrochloride (Compound A1) is the selective inhibitor for C1s protease with the Ki of 5.8 µM. C1s-IN-1 trihydrochloride inhibits cleavage of C2 by C1s with an IC50 of 85 µM, inhibits the activation of classic pathway with an IC50 of 22 µM. C1s-IN-1 trihydrochloride is the competitive inhibitor for thrombin with the Ki of 51.2 µM[1].
Molekulargewicht:
390.74
Reinheit:
99.73
CAS Nummer:
[1376162-36-5]
Formel:
C16H22Cl3N5
Target-Kategorie:
Complement System
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
