PNU-142586 (sodium), CAS [[2468637-62-7]] Preis auf Anfrage

Produktübersicht

• Artikelname: PNU-142586 (sodium), CAS [[2468637-62-7]] Preis auf Anfrage
• Artikelnummer: MCE-HY-W654323
• Hersteller Artikelnummer: HY-W654323
• Alternativnummer: MCE-HY-W654323-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

PNU-142586 sodiu) is the major metabolite of Linezolid (HY-10394). PNU-142586 can inhibit the activity of DNA topoisomerase 2-alpha (TOP2A) and DNA topoisomerase 2-beta (TOP2B). PNU-142586 interferes with DNA replication and transcription by blocking the binding of DNA to TOP2 and inhibiting ATP hydrolysis, ultimately leading to antiproliferative and cytotoxic effects, including mitochondrial dysfunction. PNU-142586 can be used to study Linezolid-induced hematotoxicity and its molecular mechanism[1].

Produkteigenschaften

• Molekulargewicht: 391.33
• CAS Nummer: [2468637-62-7]
• Formel: C16H19FN3NaO6
• Target-Kategorie: Drug Metabolite,Topoisomerase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound