PNU-142586 (sodium), CAS [[2468637-62-7]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-W654323
Supplier Catalog Number:
HY-W654323
Alternative Catalog Number:
MCE-HY-W654323-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
PNU-142586 sodiu) is the major metabolite of Linezolid (HY-10394). PNU-142586 can inhibit the activity of DNA topoisomerase 2-alpha (TOP2A) and DNA topoisomerase 2-beta (TOP2B). PNU-142586 interferes with DNA replication and transcription by blocking the binding of DNA to TOP2 and inhibiting ATP hydrolysis, ultimately leading to antiproliferative and cytotoxic effects, including mitochondrial dysfunction. PNU-142586 can be used to study Linezolid-induced hematotoxicity and its molecular mechanism[1].
Molecular Weight:
391.33
CAS Number:
[2468637-62-7]
Formula:
C16H19FN3NaO6
Target:
Drug Metabolite,Topoisomerase
Application Notes:
MCE Product type: Reference compound
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