Doxazosin (hydrochloride), CAS [[70918-01-3]] Preis auf Anfrage

Produktübersicht

• Artikelname: Doxazosin (hydrochloride), CAS [[70918-01-3]] Preis auf Anfrage
• Artikelnummer: MCE-HY-W753806
• Hersteller Artikelnummer: HY-W753806
• Alternativnummer: MCE-HY-W753806-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: UK 33274 (hydrochloride)

Produktbeschreibung

Doxazosin hydrochloride (UK 33274 hydrochloride) is a compound used to inhibit hypertension and prostate hyperplasia, with activity that inhibits postsynaptic alpha1-adrenoceptors on vascular smooth muscle. Doxazosin hydrochloride can cause vasodilation, thereby reducing peripheral vascular resistance. Doxazosin hydrochloride was found to inhibit the proliferation and migration of hepatic stellate cells in a mouse liver fibrosis model. Doxazosin hydrochloride regulates fibrosis, autophagy, and apoptosis of hepatic stellate cells by activating the PI3K/Akt/mTOR signaling pathway. Doxazosin hydrochloride also blocks autophagic flux and induces apoptosis of hepatic stellate cells[1].

Produkteigenschaften

• Molekulargewicht: 487.94
• CAS Nummer: [70918-01-3]
• Formel: C23H26ClN5O5
• Target-Kategorie: Akt

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound