Doxazosin (hydrochloride), CAS [[70918-01-3]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-W753806
Supplier Catalog Number:
HY-W753806
Alternative Catalog Number:
MCE-HY-W753806-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
UK 33274 (hydrochloride)
Doxazosin hydrochloride (UK 33274 hydrochloride) is a compound used to inhibit hypertension and prostate hyperplasia, with activity that inhibits postsynaptic alpha1-adrenoceptors on vascular smooth muscle. Doxazosin hydrochloride can cause vasodilation, thereby reducing peripheral vascular resistance. Doxazosin hydrochloride was found to inhibit the proliferation and migration of hepatic stellate cells in a mouse liver fibrosis model. Doxazosin hydrochloride regulates fibrosis, autophagy, and apoptosis of hepatic stellate cells by activating the PI3K/Akt/mTOR signaling pathway. Doxazosin hydrochloride also blocks autophagic flux and induces apoptosis of hepatic stellate cells[1].
Molecular Weight:
487.94
CAS Number:
[70918-01-3]
Formula:
C23H26ClN5O5
Target:
Akt
Application Notes:
MCE Product type: Reference compound
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