2-Propylpent-4-ynoic acid, CAS [[24102-11-2]] Preis auf Anfrage

Artikelnummer: MCE-HY-W787758
Artikelname: 2-Propylpent-4-ynoic acid, CAS [[24102-11-2]] Preis auf Anfrage
Artikelnummer: MCE-HY-W787758
Hersteller Artikelnummer: HY-W787758
Alternativnummer: MCE-HY-W787758-1UNIT
Hersteller: MedchemExpress
Kategorie: Biochemikalien
Alternative Synonym: 4-yn-VPA
2-Propylpent-4-ynoic acid (4-yn-VPA) is a HDAC inhibitor (with an IC50 of 0.5 mM against human HDAC). 2-Propylpent-4-ynoic acid also induces P-glycoprotein function, and exhibits teratogenicity, fetal growth inhibition and neurotoxicity. 2-Propylpent-4-ynoic acid shows significant stereospecific teratogenic effects, with the S-enantiomer being more teratogenic than the R-enantiomer and other analogs. The neurotoxicity of 2-Propylpent-4-ynoic acid is independent of its stereochemical structure. 2-Propylpent-4-ynoic acid has been used in studies related to the pathogenesis of colon cancer and neural tube defects such as exencephaly[1][2].
Molekulargewicht: 140.18
CAS Nummer: [24102-11-2]
Formel: C8H12O2
Target-Kategorie: HDAC,P-glycoprotein
Anwendungsbeschreibung: MCE Product type: Reference compound