2-Propylpent-4-ynoic acid, CAS [[24102-11-2]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-W787758
Supplier Catalog Number:
HY-W787758
Alternative Catalog Number:
MCE-HY-W787758-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
4-yn-VPA
2-Propylpent-4-ynoic acid (4-yn-VPA) is a HDAC inhibitor (with an IC50 of 0.5 mM against human HDAC). 2-Propylpent-4-ynoic acid also induces P-glycoprotein function, and exhibits teratogenicity, fetal growth inhibition and neurotoxicity. 2-Propylpent-4-ynoic acid shows significant stereospecific teratogenic effects, with the S-enantiomer being more teratogenic than the R-enantiomer and other analogs. The neurotoxicity of 2-Propylpent-4-ynoic acid is independent of its stereochemical structure. 2-Propylpent-4-ynoic acid has been used in studies related to the pathogenesis of colon cancer and neural tube defects such as exencephaly[1][2].
Molecular Weight:
140.18
CAS Number:
[24102-11-2]
Formula:
C8H12O2
Target:
HDAC,P-glycoprotein
Application Notes:
MCE Product type: Reference compound
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