IKP-104 is a microtubule/tubulin inhibitor (IC50 = 1.31 µM). IKP-104 arrests cells in mitosis and the M phase by inhibiting microtubule polymerization and inducing cytoskeletal microtubule depolymerization. IKP-104 inhibits the growth of mouse and human tumor cell lines. IKP-104 exhibits anti-tumor effects in mouse ascites tumors and lung cancer models. IKP-104 is useful in the research of cancers such as leukemia, lung cancer and melanoma[1][2][3][4].
Molekulargewicht:
449.90
CAS Nummer:
[114231-14-0]
Formel:
C26H21ClFNO3
Target-Kategorie:
Microtubule/Tubulin
Anwendungsbeschreibung:
MCE Product type: Reference compound1
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten